Bell Research Center for Reproductive Health and Cancer

1 ARTICLES PUBLISHED IN JoVE

Cancer Research

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Yoshihiro Koya^1,2, Hiroaki Kajiyama², Wenting Liu^1,2, Kiyosumi Shibata², Takeshi Senga³, Fumitaka Kikkawa²

¹Bell Research Center for Reproductive Health and Cancer, ²Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, ³Department of Cancer Biology, Nagoya University Graduate School of Medicine

To clarify the multistep process of peritoneal dissemination of ovarian carcinoma, the current study presents a murine experimental model of original tumor development and peritoneal metastasis via orthotopic inoculation with these tumor cells.